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Author Topic: Determining Hypo Unawareness  (Read 38 times)

Offline skb

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Determining Hypo Unawareness
« on: July 30, 2018, 08:23:04 PM »
This study attempts to determine hypoglycaemic episodes in patients who are hypo unaware by measuring glial acetate cells as a new bio marker.

https://link.springer.com/article/10.1007%2Fs00592-018-1180-5
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Offline Grammabear

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Re: Determining Hypo Unawareness
« Reply #1 on: July 31, 2018, 01:50:06 PM »
How reliable is the data gained from this study when the subjects were healthy individuals to begin with?  And why were the subjects all male, no females?  Does this mean females are not supposed to be hypo-unaware?
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"I've learned that people will forget what you said, people will forget what you did, but people will never forget how you made them feel."  ~Maya Angelou

Offline skb

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Re: Determining Hypo Unawareness
« Reply #2 on: July 31, 2018, 06:53:43 PM »
Quote
Due to known gender differences in the counter-regulatory response to hypoglycemia [18, 20, 21], study enrollment was limited to males 18–40 years old with a Body Mass Index (BMI) between 20.0 and 27.9 kg/m2, who were willing to reside on the inpatient unit for 4 days. Subjects were excluded for prior diagnosis of type 1 or 2 diabetes mellitus, fasting glucose ≥ 110 mg/dL, hyperketonuria (≥ 15 mg/dL), contraindication to MRI, current use of prescription medications, history of or current eating disorder, history of obsessive compulsive disorder, contraindication to prolonged fasting, and consumption of ≥ 10 alcoholic drinks per week.
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