Started by skb, October 21, 2018, 04:07:49 am
Quotethe team found that the strongest genetic signals in LADA were mainly shared with established variants known to be linked to T1D. However, the researchers discovered a novel locus with genome-wide significance near the gene PFKFB3. This gene codes for a protein that regulates both insulin signaling and glycolisis, the chemical reaction that yields energy from glucose. "This finding points to how variants at PFKFB3 may help to drive LADA,"